It's not a trade-off. Use of /etc/resolv.conf and port 53 is defined by historical use and by a large number of IETF RFC.

When you violate those, it is broken.

That's why systemd has such a bad reputation. Systemd almost always breaks existing use in unexpected ways. And in the case of DNS, it is a clearly defined protocol, which systemd-resolved breaks. Which you claim is a 'tradeoff'.

When a project ships an optional component that is broken, it is still a broken component.

The sad thing about systemd (including systemd-resolved) is that it is default on Linux distributions. So if you write software then you are forced to deal with it, because quite a few users will have it without being aware of the issues.