It would be a really good thing to integrate something like Safeboot (https://github.com/osresearch/safeboot), which does use TPMs. Safeboot is implemented as Bash scripts using tpm2-tools, which... I'm really not fond of. I'd rather implement the Safeboot protocol or similar from scratch in Rust or Go, or even maybe parts in C and parts in a safe language. But anyways, the idea is to enroll a host given its TPM's EKcert or the system's platform cert (if it has one), and in the process generate credentials for the host that it will be able to fetch upon attestation upon first boot and which only it can decrypt using its TPM, then after that the host can use those credentials as a root of trust with which to acquire any other necessary credentials (if any). E.g., client certificates, Kerberos keys ("keytabs"), TLS server certificates, etc.