When your normal lymphatic processes (and glymphatic processes) are slowed, or near-halted.
And at least mention terms you used.
Impairment sounds too permanent, when this is often an intermittent, “on average” sort of issue - not a complete freeze.
it turns out toxins (environmental, die-off and waste of cells from infection, dietary, lifestyle) are important to everyone,
not just vegans in Sandler movies.