C&H was the first time that I realized how authenticity resonates with people. I think people love C&H because they recognize Calvin, Hobbes, Suzie, Biff, the parents (or even Rosalyn) in themselves. Calvin often said the things that we thought only ourselves were thinking (remember the strip where Calvin is selling swift kicks in the pants for 10c because the world clearly needs it?).
Now, I see this technique work so well for business and political leaders, comics, social commentators, etc. It is a very effective technique to capture the hearts of your audience.