This legislation has a potential to "radicalize" a lot of people. I don't agree with many of the decisions by the EU, but at the end of the day the pros do outweigh the cons and in a hypothetical Brexit-like referendum I wouldn't consider agreeing with leaving.
If this passes, however, the pencil in my hand would definitely hover above the YES checkbox for a while and, actually, maybe even tick it. This alone would be enough of a straw to break the camel's back.