For sure there are some therapeutic effects when kicking someone who is stuck into totally unknown territory. But as far as I've seen most of these people want to get into a mode to understand something better (themselves, the world, spiritual things...). I think some drugs are good at creating the illusion of understanding something.

As a mathematician I can assure you that the feeling of understanding is an emotion. It's mostly disconnected from truth/false values. People can be emotionally happy, be exited and have a group feeling of understanding - but then you give them a counterexample and it turns out everything was just wrong.

A drug might be able to trigger the emotions, but the things about deeper understandings are most likely just illusions. I think I understood that when some guy who was a very simple mind (he was into sniffing glue - and bummed for alcohol) told me about his wonderful experiences of understanding the world.