Cobra is compiled, there is a big speed difference compared to Python. There are a bunch of other features you should check out once the site speeds up.
That means when the interest in the language drops to near zero again... I don't know, maybe the authors or maintainers of a web page should be warned before posting the link on Hacker News? I'm angry, because I find Cobra to be one of very nice languages that I'd like to see used more - and hn'ed site does not do any good on that front :/
I was playing with Cobra about a year ago and it was promising then - now it looks like it's almost ready for prime time. I think I'll try to use it for my next project.
If you need Python on .NET there always is IronPython, which is quite well supported. I think Cobra was made incompatible with Python syntax to emphasize that it is not Python, it has different aims and philosophy - but I can be dead wrong on this, maybe it's just because author liked some syntax better...
That being said I really don't think syntax matters that much, even if it's very similar (or very different) to something you know already. I learned and use CoffeeScript with pleasure even though it's syntax is similar - but not compatible - with Python's. Given a good syntax highlighting plugin for Vim, which I use as my editor, I have almost no problem at all with switching from Python to Coffee mode - when I end an if statement with ":" it gets highlighted as an object literal and then I instantly know it's wrong. On the other hand I use OCaml and Racket for some of my side-projects and similarly I don't miss much of Python's constructs. I think it is more important for syntax to be consistent than to be familiar or similar to something. I just don't understand marketing languages as "similar to C" in syntax, who cares?
Just because it is a nice excuse to use it on work projects, otherwise I am bound to the languages required for the project.