There's a few parts to this. Everything has to be carefully sized - power, pipe sizes, unit locations. You need to put a house's thermal profile (how much heat loss, how much air leak, how much thermal mass) along with the regional thermal profile into an engineering calculation which computes what you need.
Thermographic inspections are a thing.[1] Usual price is around $400. They're not very standardized. You get IR images of a house, which is good for finding leaks but not quantitative enough to size a heating and cooling plant.
This would be a great drone application. Fly over and around the house. Build a 3D model of the house and paint heat loss on top of it. Crunch on data to get the engineering info needed to correctly size HVAC. Also discover big heat leak points. Turn this from experienced guessing into measurement.
Then submit that data sheet to multiple sites that offer heat pumps.
Startup opportunity here.
[1] https://www.energy.gov/energysaver/thermographic-inspections