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Can someone explain this? I watched a South park episode that was all about this, but I'm not in the US so I have no idea what the reference is.

It's a meme without a lot of real meaning behind it. While it has its origins, I wouldn't say it's a "reference" to anything specific.

Ahh, thanks, so it's just a thing kids say.

Yep

It's a line from a banger Skrilla song, nothing more than that.