Not that I disagree with you, but maybe not for the reasons you say (:
As someone who used to work on the inside, us-east-1 has the biggest pile of legacy workarounds for internal AWS issues, it has a variety of legacy API behaviours that don't exist in other regions, and because everyone picks it as the default, it has significantly more pressure on contested resources (i.e. things like spot instance pools).
Plus since it's the default in all the tooling, if you ever decide to go multi-region, you'll find tons of things break right away.
Or you might use BART to come to work and you got stuck: https://www.kqed.org/news/12060687/bart-resumes-service-but-...
wish I'd already had this link in my back pocket. our industry needs to take its job, as a whole, much more seriously.