Now, I may well be naive - but isn't the point of these systems that you fail over gracefully to another data centre and no-one notices?
They make lawyers happy and they stop intelligence services to access the associated resources.
For example, no one would even consider accessing data from a European region without the right paperwork.
But yeah, that's pretty hard and there are other reasons customers might want to explicitly choose the region.
Yes, within the same region. Doing stuff cross-region takes a little bit more effort and cost, so many skip it.