It's a little bigger than what I imagine you're looking for, but the Radxa 5 ITX (not the ITX+) has 4 SATA ports, PoE+ (via a separate module), 2x2.5GbE, and the RK3588 SoC - I've been testing OpenMediaVault on it for the last couple of weeks and it's been pretty solid. If you're fine with M.2, the Radxa ROCK 5B+ has 2 M.2 M-Key connectors, the same RK3588 SoC, and PoE via a HAT bought separately.

Otherwise, there are dual NVMe HATs for the Raspberry Pi 5 but you'll be splitting a single PCIe Gen 2 lane across both drives (unless you go for the much more expensive HATs that have a Gen 3 PCIe switch on them to then share a single Gen 3 lane across them!)