One of my biggest gripes around typing in python actually revolves around things like numpy arrays and other scientific data structures. Typing in python is great if you're only using builtins or things that the typing system was designed for. But it wasn't designed with scientific data structures particularly in mind. Being able to denote dtype (e.g. uint8 array vs int array) is certainly helpful, but only one aspect.

There's not a good way to say "Expects a 3D array-like" (i.e. something convertible into an array with at least 3 dimensions). Similarly, things like "At least 2 dimensional" or similar just aren't expressible in the type system and potentially could be. You wind up relying on docstrings. Personally, I think typing in docstrings is great. At least for me, IDE (vim) hinting/autocompletion/etc all work already with standard docstrings and strictly typed interpreters are a completely moot point for most scientific computing. What happens in practice is that you have the real info in the docstring and a type "stub" for typing. However, at the point that all of the relevant information about the expected type is going to have to be the docstring, is the additional typing really adding anything?

In short, I'd love to see the ability to indicate expected dimensionality or dimensionality of operation in typing of numpy arrays.

But with that said, I worry that typing for these use cases adds relatively little functionality at the significant expense of readability.