Linux for me is all about customization and control, particularly of hardware, which you'd usually do for optimization (performance, workflow, latency, stability), which is fun if you care about optimization and efficiency, but for "good enough/I'm used to it/I'm a satisfied paying customer" I suppose there's no reason to investigate or risk. The market has poured loads of capital into satisfying PC multimedia use-case.

I'd suspect there's probably versions of all those that have been made to function basically through WINE.

If your curious, it's very easy to use it as a hypervisor, and pull out what you can, though IOMMU/SR-IOV might be tricky.

Alternatively, checking if Blender/GIMP service your use cases wouldn't even require switching...

AutoHotKey has been solved a lot of different ways, for sure.

But yeah, granular detailed control over your hardware is still the primary use-case for Linux, so if you view bad defaults, annoying install procedures, occasional show stopping bugs a hindrance rather than an opportunity, maybe it's not a strong candidate.