I've joked that if you're an old person trapped in a nursing home, one strategy to get yourself out of there is by cheeking a bunch of tylenol until you have enough, then taking them all at once. 4000mg/day starts to damage the liver. 10,000 mg can lead to liver failure. A pharmacist told me that Tylenol-induced liver failure is not a very pleasant way to die.
There are 2016/2017 tweets by @Tylenol about how the drug shouldn't be used during pregnancy: https://x.com/tylenol/status/839196906702127106 https://x.com/tylenol/status/773897927420841985
This thread was started by someone who commented on how Eric Engstrom (the co-creator of DirectX) accidentally euthanized himself with Tylenol: https://news.ycombinator.com/item?id=25424258
FDA: Acetaminophen one of the most dangerous drugs on the market, March 26, 2023: https://news.ycombinator.com/item?id=35309904
"[...] we can get away with things that we wouldn't be able to get away with nowadays. There's a lot of stuff that's like this; for instance, paracetamol/Tylenol would probably not be approved if it was introduced now because it's really easy to accidentally overdose on." August 6, 2012: https://news.ycombinator.com/item?id=4347943