Correct me if I'm wrong, but I think what they're getting at is that they're expecting an evolution in malware because of this. i.e. your typical "stupid"/mass malware will slowly grow obsolete, maybe even drop off the map and be replaced with more intelligent forms of the same thing, using concepts from that of Flame or better.

So should malware authors all figure out what Flame (or other more advanced malware) is doing, and how to do it themselves, eventually current day AV _will_ be useless.

No?