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Comment by lr4444lr | Hacker News Reader

I occasionally use CBN for sleep, never THC, so maybe it's different, but I quickly develop a tolerance, like within a week of daily use and have to cease for many days or a few weeks to get any further benefit at all.

As I read, the endocannabinoid system in the brain is pretty homeostasic.

Does something similar happen with cannabis munchies subsiding to people who ingest THC or whole leaf products daily?

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Anecdotally yes. I'm a very occasional user now and get insane munchies but when I was using it differently I felt that tolerance built quickly and I stopped having munchies once it did. Not even quite daily use either like 3-4/week. Another comment elsewhere in here describes the same experience.

I've been taking CBD daily in the evening for sleep (can't find a quality source if CBN where I live - I am interned tho, the research is compelling for sleep) and I find it can act almost like an appetite suppressant.

I took CBD twice and both times it worsened my sleep, so I really wanted a pure CBN product.

Not sure where you live, but this is what I use for CBN: https://www.charlottesweb.com/products/stay-asleep-cbn-gummi...

One gummy (10mg) works for about 2-3 nights, then I get another 2-3 nights effect with 20mg. Then I have to cease taking it for several days.

Alas, they won't ship that product to where I live.

Yes, but it remains a good anti-emetic.

Once you become a heavy user it no longer reliably triggers appetite, maybe because you get better at recognizing the hunger is fake and focus on other aspects of the high.

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