The user profiles was slow to set up and not having shared filesystem between the user profiles creates friction. But I love that I can effectively sandbox my work apps, sandbox the Zuck apps etc, with different VPN profiles for each user.
Getting a burner google account (for gplay services) is a PITA if you are determined to get a clean slate from Googles tracking. Gplay is the only safe way to get certain apps at the moment, and make certain apps pass the device integrity checks.
I suspect one of the biggest barriers to mass adoption will be the fact that tap to pay doesn't work. IIUC apple/google pay are generally considered a privacy and security improvement over physical cards, since you don't give every merchant your actual card number.
Overall love the project and really nice to see such high quality open source software.