Not really? On something like Xenforo2, there's a setting that makes a new account's posts invisible until that account is manually approved by a mod - in conjunction with the spam prevention tools - https://xenforo.com/docs/xf2/spam/#content - we really don't need to do much work.

Because all new accounts need to be verified by an actual human, we can filter out 99% of spam before other users see it, and between a dozen mods for a community of 140k people we only need to spend ~15 minutes a week cleaning out spam.