This is significant but also in line with standard Russian behavior as we know it from the last century; they will push as long and as far as they can. Zero respect for normal diplomatic relations or smaller nations. The entire eastern half of Europe has plenty of experience with this.
There need to be some reprisals for this incursion, otherwise more Shaheds will "arrive" by "bad luck", of course.
A no-fly zone over a stretch of Western Ukraine, enforced by NATO air power, would be in place. Manned Russian aircraft don't operate there, only drones and missiles.