The issue with all the layouts for me is the challenge of buying a device with them. I use Neo2 daily (I changed due to injuries and it has helped me recover and still be able to type) and the only method I enjoyed was getting a blank keyboard on a Framework Laptop (as stickers all over the place is not for me) and I bought an MNT Research Keyboard in a Neo2 layout. Regular usage is key, and a desire/need to change keyboards. I previously tried to switch to Dvorak on one of those Typematrix keyboards and never kept it up as the pain of switching wasn't worth it.

I can still use qwerty due to muscle memory when I need to, I just find myself making dumb mistakes initially. As others have said, typing speed is not a focus due to my ability to only think at a specific pace.