If you are working in Healthcare or security wouldn't Onedrive be disabled and therefore it can't autosave to the cloud?
A reasonable policy for dealing with this variety is to default to not transferring anything you're working on outside the relevant parts of your organisation - including use of cloud services - and then enable specifics on a per-client basis according to need. It's like the principle of least privilege. But if you operate that way then any software that quietly starts sharing things without explicit permission is a big problem.
And if this change will affect home users who don't have professionally managed systems as well then the same moral hazard applies. I don't think it's OK to push people into sharing their personal data online without understanding what they're doing and the potential consequences.