If you are a letsencrypt user, then it is nearly impossible to see (even with CT logs) that there was a malicious interception. From a website operator it looks like a pretty standard renewal as Letsencrypt has a short validity duration anyway.
Add on top of that in the US they have access to easy and non-BGP entry points to reroute traffic (Google DNS, Cloudflare DNS).
They can intercept in practice all Cloudflare and all Letsencrypt sites (except the Letsencrypt they also need cooperation of a friendly DNS and have a very theoretical little risk to get caught in CT logs).
Big sites like Meta or Google or Amazon already have to cooperate and intercept internally so in practice almost all western internet is interceptable rather easily.
There is zero world where US gov would want to stop that.
The tech guys working for the NSA are from being idiots, and it would be insulting to even consider that. They would fight to protect Letsencrypt