I know Go and Rust are the belles du jour, but this kind of thing really hampers integrators' ability to support platforms other than x86-64 and armv8. In my particular case, it results in me being unable to build software that depends on pyca/cryptography on platforms like s390x, which makes me sad. It also makes development environment management, including CI/CD pipeline maintenance, that much more complicated. It was already bad enough when I was trying to compile binary distributions on Windows, and that was just with the Visual C++ toolchain mess that is the Microsoft development experience.