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could this be used in a guitar amplifier circuit?

that is one of the few domains where valve technology still holds a superior position, in terms of product lines

I expect so. Pull up a spec sheet for the Nuvistor in question and see if meets the needs. Triode or pentode ... there are guitar amps and topologies for either. Depending on their specs, they might not work in the power amp stage of a guitar amp but perhaps the pre-amp — so you could get a hybrid.

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