This shows up in a lot of ways: sensory (can't just filter out the tag on the back of your shirt), interests (can't recognize that you're spending just a liiiitle too much time on that model train), food (don't categorize trying new foods as interesting, so you don't), etc. But human socialization is incredibly complex, and while many of us can do decently well at learning it, imagine trying to get a grip on social cues without being able to tell what's relevant and what's not. Sounds pretty bad, doesn't it?
It also is a working theory that well matches my experience with the autistic people in my life. "Deficits in cognitive empathy/ inability understand intuitively what other people are thinking", aka "theory of mind", is a really good description of how things are often difficult, and I think "different stimulus input filter" is a pretty good hypothesis for how it might arise.