As 'GeekyBear' implies in a sibling comment, valgrind works with an emulation of an ideal processor rather than directly on the actual CPU. Sometimes this gives you a good idea of how the program will actually run, and sometimes it doesn't. As processors became more complex, it got farther and farther from the truth. Personally, I started in the Valgrind era and stopped using it as soon as better tools using native instrumentation became available. If Apple's approach works as well as described, it is much better than anything from that era.