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Comment by CGMthrowaway | Hacker News Reader

How does this compare with nano-hydroxyapatite, which is the current rage in toothpaste innovation and remineralization?

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nHA is prohibitively expensive to produce and the most effective process that produces the smallest particles is patent-protected by Sangi, and therefore many nHA toothpaste brands only contain a fraction of the concentration used to produce the effective results reported in academic studies (1-2% instead of 10%).

If keratin toothpastes can be produced more economically they could be a better option for mass adoption. For anyone who wants to try nHA toothpaste for remineralization, I can only recommend Sangi Apagard Royal toothpaste ($$$) but it does work quite well when used as directed.

bah it's like $15-20 a tube that will last a couple months. That's nothing to most people on hackernews

More expensive than conventional fluoride toothpaste available in the US but I agree it is a small price to pay when considering the benefits

1 tube lasts me nearly 3 months. Eat at home one time and you're good. I'm not saying people who are living paycheck to paycheck where $15 makes a big difference between choosing rent or food or toothpaste, but that should have been obvious I think. Fluoride works of course, but I think in the long run nHAP works better and is probably better for your teeth. I know it fixes all my sensitivity issues and I haven't had a cavity in 10 years since I started it, was using novamin before that.

novamin* and before that fluoride which I had occasional small cavities with.

First time I've heard about apagard royal. In India it costs ₹5145 or $60 appprox.

Thats... substantially more expensive than regular toothpaste. Which costs ₹100-₹200 or $2-3.

Regular toothpaste is just detergent (SLS) with sand (silica) and smelting waste (fluoride) added. Not surprised

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