It's telling how little discussion this post is generating on HN. Perhaps a little too uncomfortable for a large portion of the crowd?
If and when people start asking themselves these questions, their only options are to rationalize away the harm their work has done entirely, engage in moral relativism, or consider "the big picture" at a zoom-level where nothing ever really matters.
And no gods no masters is the sort of thing you might see someone say right before they become the leader, ban religion, and cause mass starvation.