You can only EQ speakers and headphones as far as the transducer can still respond accurately to the signal you're sending it. No amount of EQ will give the Sennheiser HD-600's good sub-bass performance because the driver begins to distort the signal long before you've amplified it enough to match the Harman target at a normal listening level.
DSP is a very powerful tool that can make terrible speakers and headphones sound great, but it's not magic.