Watch out, there is no reliable Mouse Model for Alzheimer's. I was deeply involved with mouse models at some point before quitting my phd in neuroscience and I quite remember that.
Not a causative finding in humans but darn interesting
Even if they did you'd have to run huge samples then do post testing necropsies to see which mice had AD which which didn't, then filter your data, then try to find results in what remains.
Otherwise you can inject the mice with a chemical known to cause AD, which is not reliable on it's own, so you can get genetically modified mice which express _some_ of the known plaques and misfolds that are associated with human AD.
Animal testing is still, largely, a very unethical and cruel affair. AD testing in mice is especially fraught with hazard.