It took me like half an afternoon to get set up for my workplace's monorepo, but our stack is pretty much just Python and MongoDB so I guess that's easier. I agree, it's a significant trade-off, it just enables a very convenient workflow once it's done, and stuff like having it make 4 different versions with no speed loss is mind-blowing.
One nice perk on the ChatGPT Team and Enterprise plans is that Codex environments can be shared, so my work setting this up saved my coworkers a bunch of time. I pretty much just showed how it worked to my buddy and he got going instantly