Everyone who is comparing Anaconda and conda to Astral and uv is missing that the conda ecosystem is language-agnostic while uv is python specific. uv won't help you install gfortran, for example. It is not a replacement, unless you only do python (and use at most common non-python libraries that are available on PyPI).
On the other hand you don't have to use anything associated with Anaconda to use the conda ecosystem. Alternative package managers like mamba and pixi rely on the conda-forge channel instead. Pixi in particular (https://pixi.sh/) is sort-of the uv for the conda ecosystem workflow-wise, and works pretty well if you want that.