This would require massively more power than the Mac Studios.
Edit: And also, to get even half as much memory, you need to spend $10k. If you want to host actually-large LLMs (not quantized/distilled versions), you'll need to spend close to that much. Maybe you can get away with 256GB for now, but that won't even host full Deepseek now (and I don't know if 512GB either, with OS/etc overhead, and a large context window).