This is so frustrating to me. Why not just google it before you think you know more about this than someone studying it for ten years? Two things can change receptor density: time and dose.
A Single Dose of Psilocybin Increases Synaptic Density and Decreases 5-HT2A Receptor Density in the Pig Brain
https://pubmed.ncbi.nlm.nih.gov/33467676/
This is exactly why psychedelics last longer than prozac. It has less to do with half life and more to do with dose.
How is the mechanism not at least comparative to prozac since it is well know they both effect serotonin? The risk with psilocin is exactly the dose, as many people find out. And you thing there are not cardiac side effects from psychedelics?
A Case of Prolonged Mania, Psychosis, and Severe Depression After Psilocybin Use: Implications of Increased Psychedelic Drug Availability
https://psychiatryonline.org/doi/full/10.1176/appi.ajp.22010...
Worsening suicidal ideation and prolonged adverse event following psilocybin administration in a clinical setting: case report and thematic analysis of one participant's experience
https://pmc.ncbi.nlm.nih.gov/articles/PMC11698204/
Safety First: Potential Heart Health Risks of Microdosing
https://petrieflom.law.harvard.edu/2022/04/13/safety-first-p...