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Has anyone here had experience using plasma donation as a way to reduce their blood PFAS concentration? I know it's an imperfect solution but I feel like it's the only way to have a measurable impact on ones levels beyond replacing all the plastic in the kitchen, being cautious of water and food sources, etc.

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There has got to be a less zero-sum solution than donating to someone else your own PFAS contaminated plasma

Bloodletting comes to mind, then

I guess the ancients were on to something when they used to let out the bad humors

They are not receiving plasma (or plasma products) because their short-term future looks so rosy - by their metrics, it's almost certainly positive-sum.

If they survive they can just donate their own plasma and PFAS later. One of the rare instances where a pyramid scheme makes sense. Every generation has a larger pool of untouched blood in which to hold our PFAS.

Human biological products (esp incl blood products) are a significant export product from the USA. Won't help Europe though because EU is one of the biggest importers.

I tried it to lower PFAS repeatedly and I can’t say I felt any better or worse from doing it. I don’t have any measurements though of PFAS before and after. Giving plasma repeatedly definitely made me feel like crap until I stopped though.

I think this assumes you would feel the effect of PFAS in the first place. What's scary to me is we're just not evolved to feel PFAS at all.

Do plasma donations remove more PFAS than other types of blood donation? I donate whole blood regularly, but have never measured my PFAS levels. As far as I know there isn't great data yet on whether it makes a big difference.

The firefighter study seemed pretty conclusive that plasma donation lowered it much more.

https://pmc.ncbi.nlm.nih.gov/articles/PMC8994130/

Do we know if it's possible to filter plasma for PFAS to avoid transfering it to others?

I'd love to know as well. I assume there's already some amount of treatment or measurements made before utilizing the plasma. Obviously it's no good taking your problem and pushing it to someone else, but on the other hand, I'd take plasma with PFAS over no plasma if I needed it.

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