IMO you're worrying about the wrong thing right now. Build your API and application without any backend persistence. Make sure your API works. This will result in a nice data API for your backend that you can then plug into various tools.

Use this to test and play with and empirically figure out what the best persistence layer is for your app. There's no possible way you know at the beginning of the app what persistence is best for your app, so don't make that decision yet.