Hacker News Reader

Comment by negativepanda | Hacker News Reader

Can you give some examples of the stimulants?

Modafinil 50-100mg or micro dose of long release amphetamine like Vyvanse.

Was just about to say this, Modafinil is my stimulant drug of choice. 100mg. Really smooth and lasts all day. I do need to take amitryptiline to help sleep but I have noise intolerance related sleep issues anyway and the combination of the two meds is complementary. My only regret is not starting sooner - I had a rather anti drug bias and saw needing medication as a weakness.

Just an anecdote, but Modafinil is one of the worst stimulants I have tried. It’s great as a one-off tool for something like staying awake to drive late at night, but every time i have taken it I get intense depression and aggravation for the next 2 days. It’s really strange. Things that normally do not worry me cause great mental suffering. If it wasn’t for that and the deep sleep impact, it would be great. I read the half life is ~16 hours.

AFAIK highly depends on the person, I've given 1/4 or 1/2 doses to people and the most common reaction is that it is like a coffee. It seems the strong reactions are a minority of users. Specifically for me, I have long term dopamine dysregulation, so it hits really strong. Without the amitriptyline there is no way I could say on it.

Any dopamine booster (agonist / reuptake inhibitor) has wildly different effects on different people. Or across different times in their life. Anecdotes are good to share, because they illuminate the variety of experiences that one should be prepared for.

Even Vyvanse vs Adderall XR are reported to have markedly different effects on the same person -- and after metabolic conversion, they're supposed to be the same active ingredient with fairly similar time release duration.

Modafinil and armodafinil I find to be excellent at getting rid of tiredness. I find for me if I take too much, I’ll get nausea that’s only curable by a sleep cycle. Armodafinil tends to last much longer.

The downside I’ve noticed is that one side effect many people don’t realize is how it affects the body for some people. It can cause increased blood pressure among others - which can lead some people to feel anxious.

Body follows mind, mind follows body.

(As in my body feels anxious, so I must be anxious ).

I personally find the effects from Modafinil to be kind of like caffeine but with less side effects / longer lasting / more effective.

I thought that these are only accessible illegally or for treatment of specific conditions like ADHD or narcolepsy.

Is there some way to legally get it for the use being discussed here?

Reply on news.ycombinator.com