Diabetes type 1 is quite well manageable if you have a CGM sensor and inject insulin regularly.

But if a person with dementia tends to peel of sensors, gets aggressive when getting injections etc. this might not work. And an unmanaged diabetes can be deadly.

Not sure how these approvals work in that case, but this groups of people might be the first that can benefit from a treatment like this.

1. It was a preexisting neurodegenerative condition that may have been worsened by the immunosuppression.

2. It is Vertex. They have a colorful history...