In the video you linked, I think she was being hyperbolic in order to stress the level of support that the US has for Israel. I don't think she meant it literally.
If the US's support for Israel ever hurt the USA in places that it genuinely cared about, then I think you'd see its support for Israel diminish or even dissipate. As it stands support for Israel is very convenient for the US industrial military complex and the USA's long-term strategic objectives in the Middle East which IMHO are large factors in its willingness to support it.