As an American living in Europe for the last decade: there are actually quite a few small tech companies that are quite strong in their regions. I’m thinking of companies like Allegro.pl, which IMO is better than Amazon.
The problem seems to be that there is no real coherence to expanding local companies beyond their origin countries. Partially because of other competitors, which each country wants to promote their own, and partially because the whole infrastructure for serving ~30 states is a headache.
IMO major benefits would come from investing heavily into translation AI tech. Europe will never have one main language, and so it won’t have the single unified cultural market that China or the US have. But that can be reduced dramatically to make it as seamless as possible.