I for instance find Python the most horrible language + ecosystem outside the js ecosystem (but I like js the language more and that's saying something), so I would always opt for lisp (or pen + paper) over Python. R / Rstudio are nice though.
I don't think it really tracks either; Lisp is quite ergonomic for this type of thing and, if you have been doing it for a while, you'll have your own tooling to work faster/more efficient in that lisp and of course, the comparison falls down then as the swiss knife now has a chainsaw option which is as good or better than other options to cut down trees.