Vibe coding Common Lisp could probably work well with additional tool support. Even a good documentation lookup and search tool, exposed in an AGENTS.md file, could significantly improve the problem Joe ran into of having the code generate bogus symbols. If you provide a small MCP server or other tool to introspect a running image containing your application, it could be even better.

LLMs can handle the syntax of basically any language, but the library knowledge is significantly improved by having a larger corpus of code than Common Lisp tends to have publicly available.