If humanity overall wins out, the next 20-30 years will see industries we can barely imagine grow to maturity. From electric driver-less cars, to new forms of power generation (even fusion), new building methods, new education, and vast mega-cities will spring out of nowhere.
In the West, in the rest of the world, we will see vast demand for things that are barely off the drawing board. And they will need support industries, innovating widgets and helpful doo-hickies.
All of which will take specialised knowledge, innovation and investment. Just what VCs are supposed to do.
(PS I strongly suspect Fred Wilson already knows this, is intelligent enough to be hiring clever VCs in India, China Sudan, and doing presumably cleverer things than I suggest.
But it annoys me that the article seems mostly - oh no! cloud is cheap, so there are no companies anymore anywhere in the world that need high risk investment. Gaaahh!)
Here is one that is a perfect example: http://www.ted.com/talks/donald_sadoway_the_missing_link_to_...
Edit: added link, minor fixes