Genetic differences across Africa shouldn't be surprising when you consider how huge Africa really is. Africa is about as big as the US, China, and Europe combined.
(* who mattered. There were earlier migrations of hominids, but the mark they left on our genetics is much smaller than the influence from later migrations.)
Humans originated in Africa, so populations there have had more time to evolve and become more diverse.
200,000 years of genetic drift versus 20,000 years makes a big difference.