ISS is in a bad orbit for this sort of thing: halfway between the best orbit for Baikonur and the best orbit for Kennedy, it was a compromise which was okay because it wasn't getting that much traffic, so the penalty didn't amount to much at the scale of the budget. Using it as an orbital way-station will end up paying that compromise penalty a whole lot of times on all the launches up to the station, driving up the total value of the orbital penalty. If you are doing something big enough in space that you can afford to keep the ISS in operation (1) then you are probably better off building your own platform in the right orbit for your launch site. (2)
Also, repeated dockings and undockings (as you assemble the mass driver and then use it) will ruin any microgravity experiments you might want to run, so you can't really combine "base station for deep space exploration" and "science lab" missions, you really need the station to be focused on one or the other.
1: The main problem ISS has is political, not technological. By design you need the US and Russia to cooperate to keep it operating, and that made a lot of sense in the 1990s, and has fallen apart over the past decade.
2: Orbital plane changes- to move ISS to the right orbit for a specific launch site- are hideously expensive in LEO. GEO satellites often find it cheaper to raise their apogee out to near the moon, make the necessary plane change way up high, and then drop the apogee again when they get to perigee, rather than make the plane changes in LEO. (ISS can't do that.)