"The Challenge" ("Vyzov" in Russian), is a 2023 space drama film shot on the International Space Station. It's the first feature-length film with actors shot in space. According to its IMDB page, the movie follows a surgeon who flies to the ISS to save a cosmonaut who suffers a heart attack.
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https://www.floridatoday.com/story/news/2025/05/21/tom-cruis...