This one is easy: run0 is not implemented in a memory-safe language, but in C. It is likely to be hit by exploitable memory-handling bugs, like the rest of systemd, as has happened multiple times before.
It’s not that simple.
And if we're talking about memory bugs (which we were up to now), then definitely no.
But run0 is new C code anyway so I don't see how your claim is relevant.