Vancouver and Toronto were very often used as stand-ins for shows based in places like Chicago, Seattle, NYC and many others. Might still be, but I barely consume that sort of media nowadays.
It made watching TV shows like Stargate SG1 additionally amusing though -- every planet they visited was basically some location near Vancouver. Me and friends used to joke about how much like carcinisation is a thing in evolution, in the Stargate universe all planets eventually ended up looking like British Columbia.