By the sound of your question I will guess you want to make a website for a small or medium sized organization? jQuery is probably the only "framework" you should need.

If they are selling anything on their website, it's probably going to be through a cloud hosted third party service and then it's just an embedded iframe on their website.

If you're making an entire web shop for a very large enterprise or something of similar magnitude, then you have to ask somebody else than me.